Neonatal inhibition of androgen activity alters the programming of body weight and orexinergic peptides differentially in male and female rats
Date
2024Citation
Carrillo, B., Fernandez-Garcia, J. M., García-Úbeda, R., Grassi, D., Primo, U., Blanco, N., Ballesta, A., Arevalo, M. A., Collado, P., & Pinos, H. (2024). Neonatal inhibition of androgen activity alters the programming of body weight and orexinergic peptides differentially in male and female rats. Brain Research Bulletin, 208. https://doi.org/10.1016/j.brainresbull.2024
Abstract
The involvement of androgens in the regulation of energy metabolism has been demonstrated. The main objective of the present research was to study the involvement of androgens in both the programming of energy metabolism and the regulatory peptides associated with feeding. For this purpose, androgen receptors and the main metabolic pathways of testosterone were inhibited during the first five days of postnatal life in male and female Wistar rats. Pups received a daily s.c. injection from the day ...
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Document type
journal article